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The Significance of T2-Weighted, Fast-Spin Echo Magnetic Resonance Imaging Scan in a Screening Test for Patients with Acoustic Tumor

Other Title
청신경종양의 선별검사로서 T2-Weighted, Fast-Spin Echo Magnetic Resonance Imaging Scan의 유용성
박, 기현; 박, 홍준; 전, 영명; 정, 연훈
Taehan Ibi Inhukwa Hakhoe chi, 43(3):265-271, 2000
Journal Title
Taehan Ibi Inhukwa Hakhoe chi; Journal of the Korean Otolaryngological Society; 대한이비인후과학회지
Background and Objectives : Although auditory brainstem response (ABR) has been the screening test of

choice, recent studies showed that ABR had only 63% sensitivity and 64% specificity in detecting small

acoustic tumors when compared with the magnetic resonance imaging (MRI) scan. Full MRI scans with

gadolinium enhancement are highly accurate at detecting these lesions, but these are time consuming and

expensive. The purpose of this study is to evaluate the effectiveness of T2-weighted, fast-spin echo

(FSE) MRI scan as a screening test for acoustic tumors by comparing it with the full MRI scans with

gadolinium enhancement.

Patients and Methods : From January 1995 through March 1999, 293 patients underwent full MRI scans

with gadolinium enhancement as well as T2-weighted FSE MRI to rule out the possibility of acoustic

tumor. All patients received pure tone audiograms, and 154 patients received speech audiograms. Speech

discrimination scores below 60% were considered abnormal, and ABR was ordered to 65 patients. The

interaural latency difference for wave V greater than 0.2 msec was considered abnormal.

Results : On the basis of detection by T2-weighted FSE MRI scan and gadolinium-enhanced MRI scan,

11 of 293 cases were determined to be acoustic tumors. There were 7 tumors which were 1.5 cm in

diameter, and 3 cases of normal ABR, which were all less than 1 cm in diameter. T2-weighted FSE MRI

scan had 100% sensitivity and 99.6% specificity, whereas ABR showed relatively low sensitivity (72.7%)

and specificity (33.3%).

Conclusion : T2-weighted FSE MRI scan was so sensitive in detecting acoustic tumors that its

effectiveness was comparable to that of full MRI scans with gadolinium enhancement. T2-weighted FSE

MRI scan also exhibited rapid performance time and demanded low cost. However, ABR had low

sensitivity for acoustic tumor, especially for small tumors of diameter less than 1 cm. Therefore,

T2-weighted FSE MRI scans are considered as a cost-effective screening tests for early detection of

acoustic tumor.
Fast-spin echoMagnetic resonance imagingAcoustic tumorAuditory brainstem response
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Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
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