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Endometrium from women with endometriosis shows increased proliferation activity.

Authors
Park, JS; Lee, JH; Kim, M; Chang, HJ; Hwang, KJ; Chang, KH
Citation
Fertility and sterility, 92(4):1246-1249, 2009
Journal Title
Fertility and sterility
ISSN
0015-02821556-5653
Abstract
Examination of 631 infertile women, including 434 women with endometriosis and 197 without endometriosis, revealed an increasing incidence of endometrial polyps, especially in the test subjects with endometriosis, and advanced stages of endometriosis. Expression of Ki-67 and Bcl-2 proteins and MTT assay results were significantly higher in endometrium of patients with endometriosis than in patients without endometriosis. These showed increased proliferation activity and cell proliferation markers not only clinically but also pathologically.
MeSH terms
AdultBiological Markers/metabolismCase-Control StudiesCell Proliferation*Endometriosis/metabolismEndometriosis/pathology*Endometrium/metabolismEndometrium/pathology*FemaleHumansKi-67 Antigen/metabolismPolyps/pathologyProto-Oncogene Proteins c-bcl-2/metabolismUterine Diseases/metabolismUterine Diseases/pathology*
DOI
10.1016/j.fertnstert.2009.04.025
PMID
19501353
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Science
AJOU Authors
김미란황경주장기홍
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