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Clinical Analysis of Eight Cases of Mucormycosis

Other Title
Mucormycosis 8예의 임상적 고찰
Authors
김, 현준; 정, 연훈; 조, 민정; 백, 성수
Citation
Imsang ibi inhukwa, 15(1):134-138, 2004
Journal Title
Imsang ibi inhukwa; Journal of clinical otolaryngology, head, and neck surgery; 임상이비인후과
ISSN
1225-0244
Abstract
Background and objectives:Invasive fungal sinusitis can present as either an indolent or fulminant process that primarily affects immunocompromised individuals. Rhinocerebral mucormycosis with intracranial involvement has a high mortality. Materials and Method:Clinical characteristics of eight cases of mucormycosis in patients were analyzed retrospectively and previous reports in the literature were reviewed. Results:We treated the patients with correction of underlying disease, wide local excision, debridement of all involved and devitalized oral, nasal, sinus, and orbital tissue and intravenous amphotericin B. Three patients survived and five patients died. Conclusion:Mainstays of treatment include antifungal agents and radical resection of necrotic tissue. Reversal of the underlying medical condition, when possible, is a critical part of the management. The favorable outcome was attributable to early diagnosis and management of focal areas of mucormycosis.
Keywords
MucormycosisSinusitis
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
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