A CASE OF VASOOCLUSIVE CRISIS DUE TO SICKLE CELL DISEASE

Abstract

The sickle cell disease are a group of hemoglobin disorders characterized by red cells that un­dergo sickle shape transformation when they are deoxygenated. Sickle cell disease is transmit­ ted as an autosomal recessive trait. This unusual property, due to the polymerization of sickle hemoglobin results in anemia and vasoocclusive complication.1) The most clinically significant of these disease are sickle cell anemia, sickle cell hemoglobin C disease, and sickle cell beta thal­assemia. Symptoms of pallor, fever, abdominal and joint pain, enlargement of the liver and spleen, swelling of hands and feet first appear near the latter part of the first year of life. Intravascular sickling affects all organs. For clinical and therapeutic purposes, exacerbations may be classified as vasoocclusive or pain, aplastic, hemolytic or sequestration crisis. we experi­enced a 22 year old female patient who suffered severe multiple joint pain and back pain thought to be caused by vaso-occlussive phenomena.