Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve.
Koo, BK; Park, KW; Kang, HJ; Cho, YS; Chung, WY; Youn, TJ; Chae, IH; Choi, DJ; Tahk, SJ; Oh, BH; Park, YB; Kim, HS
European heart journal, 29(6):726-732, 2008
European heart journal
AIMS: This study was performed to evaluate the functional outcomes of fractional flow reserve (FFR)-guided jailed side-branch (SB) intervention strategy.
METHODS AND RESULTS: One hundred and ten patients treated by provisional strategy were consecutively enrolled and SB FFR was measured in 91 patients. SB intervention was allowed when FFR was <0.75. FFR measurement was repeated after SB intervention and at 6-month follow-up angiography. In 26 of 28 SB lesions with FFR or=0.75 was achieved in 92% of the lesions although the mean residual stenosis was 69 +/- 10%. During follow-up, there were no changes in SB FFR in lesions with (0.86 +/- 0.05 to 0.84 +/- 0.01, P = 0.4) and without SB angioplasty (0.87 +/- 0.06 to 0.89 +/- 0.07, P = 0.1). Functional restenosis (FFR <0.75) rate was only 8% (5/65). When clinical outcomes of these patients were compared with 110 patients with similar bifurcation lesions treated without FFR-guidance, there was no difference in 9-month cardiac event rates (4.6 vs. 3.7%, P = 0.7) between the two groups.
CONCLUSION: In conclusion, FFR-guided SB intervention strategy resulted in good functional outcomes.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :2,608,516
Total Download :1,073,104
Today View :167
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.