30 307

Cited 0 times in

Prognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction.

Park, YH; Kang, SJ; Song, JK; Lee, EY; Song, JM; Kang, DH; Kim, YH; Lee, CW; Hong, MK; Kim, JJ; Park, SW; Park, SJ
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 21(3):262-267, 2008
Journal Title
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
OBJECTIVES: We sought to test whether longitudinal strain (LS) can be a useful predictor of left ventricular (LV) remodeling after reperfusion therapy in acute myocardial infarction.

BACKGROUND: Predicting LV remodeling based on quantification of regional contractility remains an elusive goal of echocardiography.

METHODS: In 50 patients with anterior-wall acute myocardial infarction, the peak systolic velocity and LS were measured by Doppler tissue imaging (LS(DTI)) and speckle tracking imaging (LS(2D)) at 7 LV segments of left anterior descending coronary artery territory after primary reperfusion therapy. LV remodeling was defined as an increase in LV end-diastolic volume of greater than or equal to 15% at follow-up echocardiography.

RESULTS: A total of 22 patients showed LV remodeling, who had significantly lower baseline ejection fraction, LS(DTI), and LS(2D), and higher wall-motion score index and peak creatine kinase-MB with shorter deceleration time of early diastolic mitral inflow than those without LV remodeling. LS(2D) (odds ratio [OR] = 1.307, 95% confidence interval [CI] = 1.082-1.579, P = .005) and LS(DTI) (OR = 1.430, 95% CI = 1.152-1.776, P = .001) were independent predictors of LV remodeling. During clinical follow-up of 18.3 +/- 9.0 months, death or congestive heart failure developed in 11 patients (22%); LS(2D) (OR = 1.455, 95% CI = 1.142-1.852, P = .002) and LS(DTI) (OR = 1.436, 95% CI = 1.093-1.888, P = .009) were independent predictors.

CONCLUSIONS: LS immediately after primary reperfusion therapy is an excellent predictor of LV remodeling and adverse events in patients with anterior-wall acute myocardial infarction.
MeSH terms
Echocardiography/methods*FemaleHumansMaleMiddle AgedMyocardial Infarction/complicationsMyocardial Infarction/surgery*Myocardial Infarction/ultrasonography*Myocardial Reperfusion*PrognosisReproducibility of ResultsSensitivity and SpecificityTreatment OutcomeVentricular Dysfunction, Left/etiologyVentricular Dysfunction, Left/surgery*Ventricular Dysfunction, Left/ultrasonography*
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
강, 수진
Full Text Link
RIS (EndNote)
XLS (Excel)


해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.