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Practice patterns of Korean urologists for screening and managing prostate cancer according to PSA level

DC Field Value Language
dc.contributor.authorChung, MS-
dc.contributor.authorLee, SH-
dc.contributor.authorLee, DH-
dc.contributor.authorKim, SJ-
dc.contributor.authorKim, CS-
dc.contributor.authorLee, KS-
dc.contributor.authorJung, JI-
dc.contributor.authorKim, SW-
dc.contributor.authorLee, YS-
dc.contributor.authorChung, BH-
dc.date.accessioned2013-04-30-
dc.date.available2013-04-30-
dc.date.issued2012-
dc.identifier.issn0513-5796-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/8093-
dc.description.abstractPURPOSE: There are still debates on the benefit of mass screening for prostate cancer (PCA) by prostate specific antigen (PSA) testing, and on systemized surveillance protocols according to PSA level. Furthermore, there is a paucity of literature on current practice patterns according to PSA level in the Korean urologic field. Here, we report the results of a nationwide, multicenter, retrospective chart-review study.



MATERIALS AND METHODS: Overall 2122 Korean men (>40 years old, PSA >2.5 ng/mL) were included in our study (from 122 centers, in 2008). The primary endpoint was to analyze the rate of prostate biopsy according to PSA level. Secondary aims were to analyze the detection rate of PCA, the clinical features of patients, and the status of surveillance for PCA according to PSA level.



RESULTS: The rate of prostate biopsy was 7.1%, 26.3%, 54.2%, and 64.3% according to PSA levels of 2.5-3.0, 3.0-4.0, 4.0-10.0, and >10.0 ng/mL, respectively, and the PCA detection rate was 16.0%, 22.2%, 20.2%, and 59.6%, respectively. At a PSA level >4.0 ng/mL, we found a lower incidence of prostate biopsy in local clinics than in general hospitals (21.6% vs. 66.2%, respectively). A significant proportion (16.6%) of patients exhibited high Gleason scores (≥8) even in the group with low PSA values (2.5-4.0 ng/mL).



CONCLUSION: We believe that the results from this nationwide study might provide an important database for the establishment of practical guidelines for the screening and management of PCA in Korean populations.
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dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHAsian Continental Ancestry Group-
dc.subject.MESHBiopsy-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPhysicians-
dc.subject.MESHProstate-Specific Antigen/*blood-
dc.subject.MESHProstatic Neoplasms/*blood/*diagnosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHUrology-
dc.titlePractice patterns of Korean urologists for screening and managing prostate cancer according to PSA level-
dc.typeArticle-
dc.identifier.pmid23074113-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481378/-
dc.contributor.affiliatedAuthor김, 세중-
dc.type.localJournal Papers-
dc.identifier.doi10.3349/ymj.2012.53.6.1136-
dc.citation.titleYonsei medical journal-
dc.citation.volume53-
dc.citation.number6-
dc.citation.date2012-
dc.citation.startPage1136-
dc.citation.endPage1141-
dc.identifier.bibliographicCitationYonsei medical journal, 53(6):1136-1141, 2012-
dc.identifier.eissn1976-2437-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Urology
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