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Kidney transplantation from a donor following cardiac death supported with extracorporeal membrane oxygenation

Lee, JH; Hong, SY; Oh, CK; Hong, YS; Yim, H
Journal of Korean medical science, 27(2):115-119, 2012
Journal Title
Journal of Korean medical science
To expand the donor pool, organ donation after cardiac death (DCD) has emerged. However, kidneys from DCD donors have a period of long warm ischemia between cardiac arrest and the harvesting of the organs. Recently, we used extracorporeal membrane oxygenation (ECMO) to minimize ischemic injury during 'no touch' periods in a Maastricht category II DCD donor and performed two successful kidney transplantations. The kidneys were procured from a 49-yr-old male donor. The warm ischemia time was 31 min, and the time of maintained circulation using ECMO was 7 hr 55 min. The cold ischemia time was 9 hr 15 min. The kidneys were transplanted into two recipients and functioned immediately after reperfusion. The grafts showed excellent function at one and three months post-transplantation; serum creatinine (SCr) levels were 1.0 mg/dL and 0.8 mg/dL and the estimated glomerular filtration rates (eGFR) were 63 mL/min/1.73 m(2) and 78 mL/min/1.73 m(2) in the first recipient, and SCr levels were 1.1 mg/dL and 1.0 mg/dL and eGFR were 56 mL/min/1.73 m(2) and 64 mL/min/1.73 m(2) in the second recipient. In conclusion, it is suggested that kidney transplantation from a category II DCD donor assisted by ECMO is a reasonable modality for expanding donor pool.
MeSH terms
Adult*Death*Extracorporeal Membrane OxygenationFemaleGlomerular Filtration RateGlucose/chemistryHumans*Kidney TransplantationMaleMannitol/chemistryMiddle Aged*Organ PreservationPotassium Chloride/chemistryProcaine/chemistryRetrospective StudiesTime FactorsTissue Donors
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Thoracic & Cardiovascular Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
AJOU Authors
이, 종훈오, 창권홍, 유선임, 현이
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