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The normal range of amniotic fluid alpha-fetoprotein in singleton midtrimester pregnancy of Korean women

Other Title
한국 여성의 정상 단태 임신에 있어서 임신중기 양수 내 alpha-fetoprotein의 정상범위
Authors
김, 준형; 변, 영지; 박, 재선; 박, 진영; 양, 정인; 김, 행수; 유, 희석
Citation
Taehan Sanbuinkwa Hakhoe chi, 50(12):1679-1684, 2007
Journal Title
Taehan Sanbuinkwa Hakhoe chi; Korean journal of obstetrics and gynecology; 대한산부인과학회지
ISSN
1738-5628
Abstract
Objective: To determine normal range of amniotic fluid alpha-fetoprotein (AFAFP) in midtrimester singleton Korean pregnant women whose pregnancy and neonatal outcomes were uneventful.



Methods: AFAFP levels were measured in midtrimester pregnancy during amniocentesis from May 1995 to September 2006 at tertiary referral center. Normal ranges were obtained from 954 singleton pregnancies in which pregnancy and neonatal outcomes were normal.



Results: Median values of AFAFP in midtrimester pregnancy were 15,800 ng/mL, 13,903.9 ng/mL, 11,408.7 ng/mL, 9,690.1 ng/mL, 6,923.4 ng/mL, 6,330.0 ng/mL, 5,295.3 ng/mL, 4,421.2 ng/mL, 3,162.5 ng/mL at 16 week, 17 week, 18 week, 19 week, 20 week, 21 week, 22 week, 23 week, and 24 week.



Conclusion:ONCLUSION: The normal range of AFAFP level in each gestational week in Korean women could be a good reference for prenatal diagnosis of various disorders.
Keywords
Amniotic fluid alpha-fetoproteinAFAFPmidtrimesternormal rangesingleton pregnancyKorean women
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
AJOU Authors
김, 준형변, 영지박, 재선양, 정인김, 행수유, 희석
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