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A Case Report of an Aldosterone-producing Adrenocortical Carcinoma

Other Title
알도스테론 분비를 동반한 부신피질암 1예
Authors
이, 유홍; 박, 태진; 김, 혜진; 김, 대중; 이, 관우; 김, 명욱; 김, 장희; 이, 태희; 정, 윤석
Citation
Journal of Korean Endocrine Society, 23(1):56-61, 2008
Journal Title
Journal of Korean Endocrine Society; 대한내분비학회지
ISSN
1015-6380
Abstract
Primary aldosteronism is a syndrome characterized by hypokalemic alkalosis and hypertension. Aldosterone-producing adenomas and bilateral adrenal hyperplasia are common causes of this syndrome. An aldosterone-producing adrenocortical carcinoma is a very rare cause of primary aldosteronism. Recently we experienced a case of an aldosterone-producing adrenocortical carcinoma. A 41-year-old female was admitted for evaluation of a retroperitoneal mass. Because of hypokalemia and a history of hypertension, we evaluated the patient for primary aldosteronism. The high ratio of plasma aldosterone to renin activity suggested the possibility of the presence of primary aldosteronism. We performed adrenal vein sampling for differential diagnosis of an aldosterone-producing tumor from a retroperitoneal mass. The adrenal vein sampling showed that the primary aldosteronism was due to an aldosterone-producing tumor from the left adrenal gland. Surgical findings indicated that the retroperitoneal mass originated from the left adrenal gland and the pathological diagnosis for the mass was an adrenocortical carcinoma. In conclusion, the results from the adrenal vein sampling, as well as the surgical and pathological findings demonstrate that this case was an aldosterone-producing adrenocortical carcinoma.
Keywords
adrenocortical carcinomaaldosteronismretroperitoneal mass
DOI
10.3803/jkes.2008.23.1.56
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
Journal Papers > School of Medicine / Graduate School of Medicine > Endocrinology & Metabolism
AJOU Authors
김, 혜진김, 대중이, 관우김, 명욱김, 장희이, 태희정, 윤석
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