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Hemodynamic Changes after Endotracheal Intubation in Patients with Cerebral Aneurysm

Other Title
뇌동맥류 환자에서 기관내삽관 시 광봉 또는 직접후두경의 사용에 따른 혈역학적 변화
윤, 채리; 박, 관식; 박, 성용; 채, 윤정; 민, 상기; 이, 숙영; 박, 형주; 노, 현주; 문, 봉기
Anesthesia and Pain Medicine, 3(1):49-54, 2008
Journal Title
Anesthesia and Pain Medicine
Background: Tracheal intubation with a lightwand intubating device (Trachlight) attenuates the hemodynamic stress response to tracheal intubation compared with a direct laryngoscope approach. We compared the effects of the direct laryngoscope (Macintosh blade) and lightwand for intubation in patients with cerebral aneurysm.

Methods: Twenty-four patients undergoing cerebral aneurysm clipping surgery were randomly divided to either the lightwand (Group 1, n = 12) or the laryngoscope (Group 2, n = 12) Group. All patients received fentanyl (2?3?g/kg), midazolam (0.1 mg/kg), and thiopental sodium (2?3?g/kg) followed by vecuronium (0.1? 0.15?g/kg).The lungs were ventilated with 3?4% isoflurane in oxygen, with 1% lidocaine (1?1.5?g/kg) administered before intubation with either the lightwand or the laryngoscope.Systolic, diastolic and mean blood pressures and heart rate were recorded continuously before and for 5 min after intubation.

Results: Systolic and mean arterial blood pressure increased significantly (P < 0.05) 1 minute after intubation, but then returned to normal within the next minute.There were no differences in hemodynamic changes between the two groups, and no complications.

Conclusions: Intubation technique did not affect hemodynamic changes in patients with cerebral aneurysm.In patients with aneurysms, appropriate anesthetic levels and pharmacologic manipulation will attenuate the hemodynamic stress response associated with tracheal intubation.
cerebral aneurysmlaryngoscopelightwandtracheal intubation
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Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
AJOU Authors
박, 관식박, 성용채, 윤정민, 상기이, 숙영문, 봉기
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