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Sulfasalazine-induced Reversible Leukoencephalopathy

Other Title
Sulfasalazine에 의한 가역적 백색질뇌병증
Authors
손, 성연; 임, 태성; 김, 동훈; 이, 성준; 최, 문희; 김, 현아; 문, 소영
Citation
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak, 28(3):218-221, 2010
Journal Title
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak; Journal of the Korean Neurological Association : neurology
ISSN
1225-70442288-985X
Abstract
A 50-year-old woman presented with a 4-day history of apathy, perseveration, and confusion. These symptoms appeared 16 days after she had started taking sulfasalazine for rheumatoid arthritis. Brain MRI showed bilateral symmetrical discoid lesions involving the corona radiata. She fully recovered 7?days after stopping the medications. Follow-up brain MRI revealed remarkable improvement of the lesions. The pathomechanisms related to sulfasalazine- induced leukoencephalopathy may be demyelinating processes due to impaired T-cell-mediated immunity.
Keywords
SulfasalazineReversible leukoencephalopathyWhite-matter diseases
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Rheumatology
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
AJOU Authors
임, 태성김, 현아문, 소영
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