88 224

Cited 0 times in

Adverse Drug Reactions in Elderly Inpatients: Comparison with Younger Patients

Other Title
노인 입원환자에서 발생한 약물유해반응의 특성
Authors
김, 정은; 견, 진옥; 진, 선민; 이, 영희; 김, 주희; 이, 현영; 박, 해심; 최, 영화; 예, 영민
Citation
Chʿŏnsik mit alrerugi, 30(3):216-221, 2010
Journal Title
Chʿŏnsik mit alrerugi; Journal of asthma, allergy and clinical immunology; Korean journal of asthma, allergy and clinical immunology; 천식 및 알레르기
ISSN
1226-8739
Abstract
Background: There have been few reports on the characteristics of adverse drug reactions (ADRs) in elderly patients among the Korean population.



Objective: To investigate the characteristics of ADRs in elderly patients compared with those in younger ones.



Method: ADRs were collected from a spontaneous reporting system at our university hospital in 2008. Characteristics including underlying diseases, duration of hospitalization, clinical manifestations, culprit drugs and number of concomitant medications were compared between the young (<65 years) and elderly (≥65 years) groups.



Result: A total of 528 ADRs occurred in 513 patients, and 120 ADRs (22.7%) occurred in 116 elderly patients. Their

mean age was 71.6 years. Antibiotics (45.8%) were the most common culprit drugs. The prevalence of ADRs due

to cardiovascular drugs was significantly higher in the elderly group (9.2%) than in the young group (2.9%, P=0.003). The most prevalent clinical types were skin manifestations (40.5%), gastrointestinal abnormalities (28.4%) and systemic reactions (23.5%) in both groups. Renal function abnormalities were significantly more prevalent in the elderly group (4.2%) than in the young group (0.5%, P=0.008). The mean number of concomitant medications was significantly higher in the elderly group (6.5±4.6) than in the young group (1.9±3.9).



Conclusion: For the early detection of ADRs in elderly patients, close monitoring of cardiovascular drug use and

renal function are recommended.
Keywords
Adverse drug reaction reporting systemsAgedCardiovascular agents
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Infectious Diseases
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
AJOU Authors
김, 정은김, 주희박, 해심최, 영화예, 영민
Full Text Link
Files in This Item:
216-221.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse