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Expression of Glucosamine-6-Phosphate Deaminase (GNPDA) in Mouse Epididymis

Other Title
생쥐의 부정소에서 Glocosamine-6-Phosphate Deaminase (GNPDA)의 발현
Authors
계, 명찬; 안, 현수; 김, 영수
Citation
Korean Journal of Andrology, 18(3):187-192, 2000
Journal Title
Korean Journal of Andrology; 대한남성과학회지
ISSN
1229-1692
Abstract
PURPOSE: To verify the expression of mouse homologue of glucosamine-6-phosphate deaminase (GNPDA) in mouse epididymis. MATERIALS AND METHODS: GNPDA expression was examined in mouse epididymis using the polyclonal antibody raised against a synthetic oligopeptide of N-terminus of mouse homologue of GNPDA. RESULTS: In Western blot, immunoreactive band of Mr. 33 kDa was detected in the cauda epididymal extracts. In immunostaining, positive signal was found in the cytoplasm and stereocillia of epithelial cells of cauda epididymal tubule, and interstitial cells of adult epididymis. CONCLUSION: Expression of GNPDA in epididymis suggests that it possibly involved in absorption and intracellular digestion of luminal contents, and the remodeling of epithelia in mouse epididymis.
Keywords
GNPDAEpididymisMouse
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Urology
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