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Relationship between Diabetic Peripheral Vascular Disease and Ankle-Brachial Index

Other Title
당뇨병성 말초혈관질환과 Ankle-Brachial Index의 상관관계
Authors
고, 보람; 김, 연경; 안, 상미; 송, 경은; 정, 선혜; 김, 혜진; 김, 대중; 정, 윤석; 이, 관우
Citation
Journal of Korean Endocrine Society, 21(5):382-388, 2006
Journal Title
Journal of Korean Endocrine Society; 대한내분비학회지
ISSN
1015-6380
Abstract
Background



Peripheral vascular disease (PVD) is a primary risk factor of foot amputation. In patients with diabetes mellitus (DM), the frequency of PVD is twice that of the general population. The ankle-brachial index (ABI) is a valuable diagnostic test for PVD. In this study, we investigated the relationship between the ABI and PVD, as well as the cutoff value of ABI in the diagnosis of PVD, and analyzed whether the ABI can be used as a predictor for amputation.



Methods



Fifty-two type 2 DM patients (31 males, 21 females) underwent peripheral angiography. PVD was defined as the complete obstruction of arteries and/or significant luminal narrowing, with collateral vessels formation, using peripheral angiography. The ABI was calculated by measurement of the segmental pressure using the Doppler method.



Results



Significant differences were observed between PVD and non-PVD patients in terms of age, systolic pressure and total cholesterol (each P < 0.05). The ABI was significantly lower in legs with PVD (P < 0.01) and an ABI less than 0.90 was adequate for diagnosing PVD. The risk of amputation was significantly increased in relation to the ABI level, and the risk of amputation was 21.5 times greater in a leg with an ABI less than 0.40 compared to 0.90 (P = 0.021).



Conclusion



ABI is a good diagnostic test for PVD and a good predictor of the need for amputation.
Keywords
Ankle-brachial indexLeg amputationPeripheral angiographyPeripheral vascular disease
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Endocrinology & Metabolism
AJOU Authors
김, 연경안, 상미송, 경은정, 선혜김, 혜진김, 대중정, 윤석이, 관우
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