16 260

Cited 0 times in

Topical Photodynamic Therapy for Treatment of Actinic Keratosis Using Light-Emitting Diode (LED) Device

Other Title
광선각화증에서 Light-Emitting Diode (LED)를 이용한 국소 광역동요법의 치료효과
Authors
이, 중선; 김, 윤전; 강, 희영; 이, 은소; 오, 충훈; 김, 유찬
Citation
Korean journal of dermatology, 43(4):469-474, 2005
Journal Title
Korean journal of dermatology; 대한피부과학회지
ISSN
0494-4739
Abstract
Background: Photodynamic therapy is a treatment modality which involves the sequential administration of a photosensitizer and light. Topical photodynamic therapy is being increasingly used for superficial non-melanoma skin cancers and their precursors.



Objective: The purpose of this study was to evaluate the effectiveness and side effects of treating actinic keratosis with photodynamic therapy using a light-emitting diode device and 20% 5-aminolevulinic acid.



Methods: Photodynamic therapy, with a 630+/-50nm light-emitting diode device and 5-aminolevulinic acid, was used to treat 12 lesions of actinic keratosis on 8 patients. The light intensity used was 50mW/cm2 , and the light dose was 100-120J/cm2 . Four weeks after 1 or 2 treatment sessions, the outcome was evaluated by histopathological findings.



Results: Complete clearance was achieved in 8 of 12 lesions after a single treatment, and in 3 of 12 lesions after 2 treatment sessions. Only 1 case showed partial response after 2 treatment sessions. Only 2 patients suffered from a stinging sensation when exposed to the light therapy.



Conclusion: Topical photodynamic therapy using a light-emitting diode is safe and effective in the treatment of actinic keratosis.
Keywords
Photodynamic therapyLight-emitting diodeActinic keratosis
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
Full Text Link
Files in This Item:
Korean journal of dermatology_43(4)_469-474.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse